Pathogenicity and Immunology; Host resistance and the immune response
Paper instructions:
In this module you have learned of the importance of the immune system in protecting against disease. For the Module 4 case assignment you will investigate the virus HIV and its effect on the human immune system, as well as important topics in infectious disease in general.
It is estimated that over 34 million people globally are living with HIV/AIDS. (http://www.avert.org) Acqiured immune deficiency syndrome (AIDS) has been described as the most common secondary immune deficiency disease in the world. Infection with the human immune deficiency virus (HIV) has been identified as the cause of AIDS. For the module 4 case assignment prepare a paper addressing the following:
Provide a general discussion of HIV/AIDS. In your paper discuss the structure of HIV and how the viral structure facilitates entry into host cells. Begin your research in your Introductory Microbiology textbook, using “Ch 11: Microbial Epidemiology,” Ch 7: Viral Effects on Cells,” and “Ch 17: Viruses and Prions” in A Concise Manual of Pathogenic Microbiology.
Include the following:
1.Discuss the function of HIV protease, integrase, and reverse transcriptase.
2.Explain how this pathogen causes disease in the host.
3.Identify the characteristics of HIV which account for its transmission. Include the basic epidemiology of this virus and its method of transfer.
4.Discuss the normal function of B-lymphocytes, killer T-lymphocytes, helper T-lymphocytes, and macrophages in the immune system. Explain how HIV affects these components of a healthy immune system.
5.Explain the function of the complement system.
6.Summarize how HIV alters normal function of the immune system.
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