Investigating the Beta-Globin Gene:Bioinformatics Map & BLAST Analysis
Paper instructions:
Include a discussion of what you learned about the beta globin gene itself, how the information in the gene gets expressed, the known variation in the gene, and the effects of different kinds of mutations. What did you learn when you compared the human beta-globin gene to the DNA of other species? Do you think this kind of comparison can give us information about evolutionary relationships? Finally, discuss what you learned about the internet resources you were introduced to in this lab. Which site did you find the most interesting, and why? Which one(s) are you most likely to visit again as a student in a Genetics course? How might researchers use these sites to understand why eukaryotic genes are divided into introns and exons, or why some thalassemias are more severe than others?
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